Human Kappa Light Chain (Kappa Light Chain) Antibody Pair (STJAP00672)
SPECIFICATIONS
ClonalityMonoclonal/Monoclonal
HostMouse/Mouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenA synthesized peptide derived from IGKC
General Information
| Short Description | This Kappa Light Chain antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Mouse/Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | 8A2/11C12 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | ELISA 1:1000 |
| Formulation | Liquid in PBS containing 0.09% sodium azide as a preservative./Liquid in PBS containing 0.01% thimerosal as a preservative. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | IGKCUniprot ID=IGKC_HUMAN" |
| Immunogen | A synthesized peptide derived from IGKC |
Additional Info
| Function | Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. |
| Protein Name | Immunoglobulin Kappa ConstantIg Kappa Chain C RegionIg Kappa Chain C Region AgIg Kappa Chain C Region CumIg Kappa Chain C Region EuIg Kappa Chain C Region OuIg Kappa Chain C Region RoyIg Kappa Chain C Region Ti |
| Cellular Localisation | SecretedCell Membrane |
| Alternative Antibody Pair Names | Immunoglobulin Kappa Constant antibody pairIg Kappa Chain C Region antibody pairIg Kappa Chain C Region Ag antibody pairIg Kappa Chain C Region Cum antibody pairIg Kappa Chain C Region Eu antibody pairIg Kappa Chain C Region Ou antibody pairIg Kappa Chain C Region Roy antibody pairIg Kappa Chain C Region Ti antibody pairIGKC antibody pair |
Information sourced from Uniprot.org