Human Kappa Light Chain (Kappa Light Chain) Antibody Pair (STJAP00672)
General Information
| Short Description | This Kappa Light Chain antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Mouse/Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | 8A2/11C12 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | ELISA 1:1000 |
| Formulation | Liquid in PBS containing 0.09% sodium azide as a preservative./Liquid in PBS containing 0.01% thimerosal as a preservative. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | IGKCUniprot ID=IGKC_HUMAN" |
| Immunogen | A synthesized peptide derived from IGKC |
Additional Info
| Function | Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. |
| Protein Name | Immunoglobulin Kappa ConstantIg Kappa Chain C RegionIg Kappa Chain C Region AgIg Kappa Chain C Region CumIg Kappa Chain C Region EuIg Kappa Chain C Region OuIg Kappa Chain C Region RoyIg Kappa Chain C Region Ti |
| Cellular Localisation | SecretedCell Membrane |
| Alternative Antibody Pair Names | Immunoglobulin Kappa Constant antibody pairIg Kappa Chain C Region antibody pairIg Kappa Chain C Region Ag antibody pairIg Kappa Chain C Region Cum antibody pairIg Kappa Chain C Region Eu antibody pairIg Kappa Chain C Region Ou antibody pairIg Kappa Chain C Region Roy antibody pairIg Kappa Chain C Region Ti antibody pairIGKC antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human Kappa Light Chain (Kappa Light Chain) Antibody Pair (STJAP00672)
This antibody pair detects human Kappa Light Chain (IGKC, UniProt P01834) and has confirmed reactivity with human samples only.
Both antibodies are supplied as affinity-purified mouse monoclonal IgG1 antibodies in liquid format at 1 mg/mL. The capture antibody (clone 8A2) is formulated in PBS with 0.09% sodium azide, and the detection antibody (clone 11C12) is formulated in PBS with 0.01% thimerosal. Neither antibody carries a conjugate or tag.
This pair has been validated for ELISA use only, at a recommended dilution of 1:1000.
Both antibodies were raised against a synthesized peptide derived from IGKC, the human Kappa Light Chain constant region.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and keep at -20°C. Repeated freeze/thaw cycles should be avoided to maintain stability.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.