| Short Description : | Recombinant-Human Kallikrein-4-protein was developed from hek293. For use in research applications. |
| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: | The activity was tested by the ability to cleave a fluorogenic substrate Boc-VPR-AMC.The specific activity was measured to be 200 pmole/ug/min NA |
| Gene Symbol: | KLK4 |
| Gene ID: | 9622 |
| Uniprot ID: | KLK4_HUMAN |
| Immunogen: | Optimized DNA sequence encoding Human Kallikrein-4-KLK4 (SER27-SER254) preprotein including a C-terminal His tag was expressed in HEK293 cells. NA |
| Immunogen Region: | SER27-SER254 |
| Tissue Specificity | Expressed in prostate. |
| Post Translational Modifications | N-glycosylated. The N-glycan structures are of complex diantennary or triantennary type, which may be further modified with up to 2 sialic acid residues. |
| Function | Has a major role in enamel formation. Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline matrix. |
| Protein Name | Kallikrein-4Enamel Matrix Serine Proteinase 1Kallikrein-Like Protein 1Klk-L1ProstaseSerine Protease 17 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Kallikrein-4 proteinEnamel Matrix Serine Proteinase 1 proteinKallikrein-Like Protein 1 proteinKlk-L1 proteinProstase proteinSerine Protease 17 proteinKLK4 proteinEMSP1 proteinPRSS17 proteinPSTS protein |
Information sourced from Uniprot.org