Human JPH3/JP-3 protein (Recombinant) (N-His) (STJP008519)

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STJP008519
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human JPH3/JP-3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: JPH3
Gene ID: 57338
Uniprot ID: JPH3_HUMAN
Immunogen Region: Met1-Ser147
Immunogen: Homo sapiens (Human)
Function Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory.
Protein Name Junctophilin-3
Jp-3
Junctophilin Type 3
Trinucleotide Repeat-Containing Gene 22 Protein
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Endoplasmic Reticulum Membrane
Single-Pass Type Iv Membrane Protein
Localized Predominantly On The Plasma Membrane
The Transmembrane Domain Is Anchored In Endoplasmic Reticulum Membrane
While The N-Terminal Part Associates With The Plasma Membrane
Alternative Protein Names Junctophilin-3 protein
Jp-3 protein
Junctophilin Type 3 protein
Trinucleotide Repeat-Containing Gene 22 Protein protein
JPH3 protein
JP3 protein
TNRC22 protein

Information sourced from Uniprot.org

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