Human JPH1 protein (Recombinant) (N-His) (STJP006032)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human JPH1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | JPH1 |
| Gene ID | 56704 |
| Uniprot ID | JPH1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Ala201 |
Additional Info
| Function | Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes. |
| Protein Name | Junctophilin-1Jp-1Junctophilin Type 1 |
| Database Links | |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneSingle-Pass Type Iv Membrane ProteinSarcoplasmic Reticulum MembraneLocalized Predominantly On The Plasma MembraneThe Transmembrane Domain Is Anchored In Endoplasmic/Sarcoplasmic Reticulum MembraneWhile The N-Terminal Part Associates With The Plasma MembraneIn Skeletal Muscle CellsIt Is Predominantly Localized At The Junction Of The A And I Bands |
| Alternative Protein Names | Junctophilin-1 proteinJp-1 proteinJunctophilin Type 1 proteinJPH1 proteinJP1 protein |
Information sourced from Uniprot.org