Human JADE1 protein (Recombinant) (N-His) (STJP009654)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human JADE1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | JADE1 |
| Gene ID | 79960 |
| Uniprot ID | JADE1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly217-Ser363 |
Additional Info
| Function | Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation. May also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling.at least in part, cooperates with NPHP4 in this function. |
| Protein Name | Protein Jade-1Jade Family Phd Finger Protein 1Phd Finger Protein 17 |
| Database Links | Reactome: R-HSA-3214847 |
| Cellular Localisation | NucleusChromosomeCytoplasmCytoskeletonCilium Basal BodyLocalizes To The Ciliary Transition Zone |
| Alternative Protein Names | Protein Jade-1 proteinJade Family Phd Finger Protein 1 proteinPhd Finger Protein 17 proteinJADE1 proteinKIAA1807 proteinPHF17 protein |
Information sourced from Uniprot.org