Human IRAK3 (Interleukin 1 Receptor Associated Kinase 3) Sandwich ELISA Kit Kit (STJE0010048)

Human IRAK3 (Interleukin 1 Receptor Associated Kinase 3) Sandwich ELISA Kit Kit (STJE0010048)

SKU:
STJE0010048
$535.28 - $726.98
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.23ng/mL
Detection Limit: 0.781-50ng/mL
Short Description : This IRAK3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: IRAK3
Gene ID: 11213
Uniprot ID: IRAK3_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed in eosinophils, dendritic cells and/or monocytes (at protein level). Expressed predominantly in peripheral blood lymphocytes.
Post Translational Modifications
Function Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors. Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells.
Protein Name Interleukin-1 Receptor-Associated Kinase 3
Irak-3
Il-1 Receptor-Associated Kinase M
Irak-M
Inactive Il-1 Receptor-Associated Kinase 3
Database Links Reactome: R-HSA-166058
Reactome: R-HSA-9020702
Cellular Localisation Cytoplasm
Nucleus
In Dendritic Cells
Translocates Into The Nucleus Upon Il33 Stimulation
Alternative ELISA Names Interleukin-1 Receptor-Associated Kinase 3 ELISA kit
Irak-3 ELISA kit
Il-1 Receptor-Associated Kinase M ELISA kit
Irak-M ELISA kit
Inactive Il-1 Receptor-Associated Kinase 3 ELISA kit
IRAK3 ELISA kit
output

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJE0016433 Human IRAK3 (Interleukin 1 Receptor Associated Kinase 3) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016433) Human ELISA
STJE0010046 Human IRAK1 (Interleukin 1 Receptor Associated Kinase 1) Sandwich ELISA Kit Kit (STJE0010046) Human ELISA
STJE0010049 Human IRAK4 (Interleukin 1 Receptor Associated Kinase 4) Sandwich ELISA Kit Kit (STJE0010049) Human ELISA
STJE0016431 Human IRAK1 (Interleukin 1 Receptor Associated Kinase 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016431) Human ELISA
STJE0010047 Mouse IRAK1 (Interleukin 1 Receptor Associated Kinase 1) Sandwich ELISA Kit Kit (STJE0010047) Mouse ELISA
!