• Human Intrinsic factor/CBLIF protein (Recombinant) (C-His) (STJP002453)

Human Intrinsic factor/CBLIF protein (Recombinant) (C-His) (STJP002453)

SKU:
STJP002453

£123.50 - £527.50
Current Stock:
Host: HEK293 Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: <0.01 EU/Mu g
Gene Symbol: CBLIF
Gene ID: 2694
Uniprot ID: IF_HUMAN
Immunogen Region: Ser19-Tyr417
Immunogen: Recombinant Human Intrinsic factor/CBLIF Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Ser19-Tyr417) of human Intrinsic factor/CBLIF (Accession #NP_005133.2) fused with a 6×His tag at the C-term
Immunogen Sequence: STQTQSSCSVPSAQEPLVNG IQVLMENSVTSSAYPNPSIL IAMNLAGAYNLKAQKLLTYQ LMSSDNNDLTIGQLGLTIMA LTSSCRDPGDKVSILQRQME NWAPSSPNAEASAFYGPSLA ILALCQKNSEATLPIAVRFA KTLLANSSPFNVDTGAMATL ALTCMYNKIPVGSEEGYRSL FGQVLKDIVEKISMKIKDNG IIGDIYSTGLAMQALSVTPE PSKKEWNCKKTTDMILNEI
Function Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis.
Protein Name Cobalamin Binding Intrinsic Factor
Gastric Intrinsic Factor
Intrinsic Factor
If
Inf
Database Links Reactome: R-HSA-3359457
Reactome: R-HSA-3359462
Reactome: R-HSA-3359463
Reactome: R-HSA-9758881
Cellular Localisation Secreted
Alternative Protein Names Cobalamin Binding Intrinsic Factor protein
Gastric Intrinsic Factor protein
Intrinsic Factor protein
If protein
Inf protein
CBLIF protein
GIF protein
IFMH protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance