• Biotinylated Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer is greater than 95% as determined by SEC-HPLC.
  • Immobilized Human Latent TGF beta 1, His Tag beta 1 at 5 Mu g/ml (100 Mu l/well) on the plate. Dose response curve for Biotinylated Human ITGAV&ITGB8, His Tag with the EC50 of 6. 6ug/ml determined by ELISA.

Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer protein (Recombinant) (C-His-Avi) {Biotin} (STJP001545)

SKU:
STJP001545

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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: ITGAV
Gene ID: 3685
Uniprot ID: ITAV_HUMAN
Immunogen Region: Phe31-Val992 (ITGAV) & Glu43-Arg684 (ITGB8)
Immunogen: DNA sequence encoding Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Protein Name Integrin Alpha-V
Vitronectin Receptor
Vitronectin Receptor Subunit Alpha
Cd Antigen Cd51 Cleaved Into - Integrin Alpha-V Heavy Chain - Integrin Alpha-V Light Chain
Database Links Reactome: R-HSA-1236973
Reactome: R-HSA-1566948
Reactome: R-HSA-210990
Reactome: R-HSA-2129379
Reactome: R-HSA-216083
Reactome: R-HSA-2173789
Reactome: R-HSA-3000157
Reactome: R-HSA-3000170
Reactome: R-HSA-3000178
Reactome: R-HSA-4420097
Reactome: R-HSA-445144
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Focal Adhesion
Alternative Protein Names Integrin Alpha-V protein
Vitronectin Receptor protein
Vitronectin Receptor Subunit Alpha protein
Cd Antigen Cd51 Cleaved Into - Integrin Alpha-V Heavy Chain - Integrin Alpha-V Light Chain protein
ITGAV protein
MSK8 protein
VNRA protein
VTNR protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance