Human INPP5A protein (Recombinant) (C-His) (STJP013472)

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STJP013472-100
£575.50
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Host: Mammalian Cells
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human INPP5A-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Conjugation: Unconjugated
Formulation: Supplied as a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: < 1 EU/µg as determined by LAL test.
Gene Symbol: INPP5A
Gene ID: 3632
Uniprot ID: I5P1_HUMAN
Immunogen Region: Met1-Val410
Immunogen: Homo sapiens (Human)
Post Translational Modifications Isoprenylation at Cys-409 is required for localization at the membrane.
Function Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. Plays a crucial role in the survival of cerebellar Purkinje cells.
Protein Name Inositol Polyphosphate-5-Phosphatase A
43 Kda Inositol Polyphosphate 5-Phosphatase
Type I Inositol 1 -4 -5-Trisphosphate 5-Phosphatase
5ptase
Database Links Reactome: R-HSA-1855183
Cellular Localisation Cell Membrane
Lipid-Anchor
Cell Projection
Dendrite
Alternative Protein Names Inositol Polyphosphate-5-Phosphatase A protein
43 Kda Inositol Polyphosphate 5-Phosphatase protein
Type I Inositol 1 -4 -5-Trisphosphate 5-Phosphatase protein
5ptase protein
INPP5A protein
5PTASE protein

Information sourced from Uniprot.org

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