Human Immunoglobulin J chain/IGJ protein (Recombinant) (His-Tag) (STJP018146)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Immunoglobulin J chain/IGJ-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | JCHAIN |
| Gene ID | 3512 |
| Uniprot ID | IGJ_HUMAN |
| Accession Number | NP_653247.1 |
| Immunogen | Human |
| Immunogen Region | 23-159aa |
| Immunogen Sequence |
Additional Info
| Function | Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers. It also helps to bind these immunoglobulins to secretory component. |
| Protein Name | Immunoglobulin J ChainJoining Chain Of Multimeric Iga And Igm |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-2168880 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Immunoglobulin J Chain proteinJoining Chain Of Multimeric Iga And Igm proteinJCHAIN proteinIGCJ proteinIGJ protein |
Information sourced from Uniprot.org