Human ILDR2 protein (Recombinant-Active) (C-hFc-His) (STJP012177)

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STJP012177-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human ILDR2-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: ILDR2
Gene ID: 387597
Uniprot ID: ILDR2_HUMAN
Immunogen Region: Leu21-Glu186
Immunogen: Homo sapiens (Human)
Function May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity. In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1.
Protein Name Immunoglobulin-Like Domain-Containing Receptor 2
Angulin-3
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Tight Junction
Nucleus
Alternative Protein Names Immunoglobulin-Like Domain-Containing Receptor 2 protein
Angulin-3 protein
ILDR2 protein
C1orf32 protein

Information sourced from Uniprot.org

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