Human IL27RA/WSX1 protein (Recombinant-Active) (C-hFc-His) (STJP012169)

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STJP012169-100
€691.88
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Covered by St John's Laboratory Guarantee

Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human IL27RA/WSX1-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: IL27RA
Gene ID: 9466
Uniprot ID: I27RA_HUMAN
Immunogen Region: Gly34-Lys516
Immunogen: Homo sapiens (Human)
Function Receptor for IL27. Requires IL6ST/GP130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and CNTFR. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.
Protein Name Interleukin-27 Receptor Subunit Alpha
Il-27 Receptor Subunit Alpha
Il-27r Subunit Alpha
Il-27r-Alpha
Il-27ra
Cytokine Receptor Wsx-1
Cytokine Receptor-Like 1
Type I T-Cell Cytokine Receptor
Tccr
Zcytor1
Database Links Reactome: R-HSA-8984722
Reactome: R-HSA-9020956
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-27 Receptor Subunit Alpha protein
Il-27 Receptor Subunit Alpha protein
Il-27r Subunit Alpha protein
Il-27r-Alpha protein
Il-27ra protein
Cytokine Receptor Wsx-1 protein
Cytokine Receptor-Like 1 protein
Type I T-Cell Cytokine Receptor protein
Tccr protein
Zcytor1 protein
IL27RA protein
CRL1 protein
TCCR protein
WSX1 protein
UNQ296 protein
PRO336 protein

Information sourced from Uniprot.org

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