Function | Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining successful pregnancy. |
Protein Name | Interleukin-22 Receptor Subunit Alpha-2Il-22 Receptor Subunit Alpha-2Il-22r-Alpha-2Il-22ra2Cytokine Receptor Class-Ii Member 10Cytokine Receptor Family 2 Member 10Crf2-10Cytokine Receptor Family Type 2 - Soluble 1Crf2-S1Interleukin-22-Binding ProteinIl-22bpIl22bpZcytor16 |
Database Links | Reactome: R-HSA-8854691 |
Cellular Localisation | Secreted |
Alternative Protein Names | Interleukin-22 Receptor Subunit Alpha-2 proteinIl-22 Receptor Subunit Alpha-2 proteinIl-22r-Alpha-2 proteinIl-22ra2 proteinCytokine Receptor Class-Ii Member 10 proteinCytokine Receptor Family 2 Member 10 proteinCrf2-10 proteinCytokine Receptor Family Type 2 - Soluble 1 proteinCrf2-S1 proteinInterleukin-22-Binding Protein proteinIl-22bp proteinIl22bp proteinZcytor16 proteinIL22RA2 proteinUNQ5793 proteinPRO19598 proteinPRO19822 protein |
Information sourced from Uniprot.org