Human IL22RA1 protein (Recombinant) (N-His) (STJP005701)

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STJP005701
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IL22RA1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IL22RA1
Gene ID: 58985
Uniprot ID: I22R1_HUMAN
Immunogen Region: Gln267-Gly565
Immunogen: Homo sapiens (Human)
Post Translational Modifications Ubiquitinated.
Function Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Protein Name Interleukin-22 Receptor Subunit Alpha-1
Il-22 Receptor Subunit Alpha-1
Il-22r-Alpha-1
Il-22ra1
Cytokine Receptor Class-Ii Member 9
Cytokine Receptor Family 2 Member 9
Crf2-9
Zcytor11
Database Links Reactome: R-HSA-8854691
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-22 Receptor Subunit Alpha-1 protein
Il-22 Receptor Subunit Alpha-1 protein
Il-22r-Alpha-1 protein
Il-22ra1 protein
Cytokine Receptor Class-Ii Member 9 protein
Cytokine Receptor Family 2 Member 9 protein
Crf2-9 protein
Zcytor11 protein
IL22RA1 protein
IL22R protein

Information sourced from Uniprot.org

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