| Function | May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth. During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD. |
| Protein Name | Interleukin-1 Receptor Accessory Protein-Like 1Il-1-Rapl-1Il-1rapl-1Il1rapl-1Oligophrenin-4Three Immunoglobulin Domain-Containing Il-1 Receptor-Related 2Tigirr-2X-Linked Interleukin-1 Receptor Accessory Protein-Like 1 |
| Database Links | Reactome: R-HSA-388844Reactome: R-HSA-9007892 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmCell ProjectionAxonDendriteMay Localize To The Cell Body And Growth Cones Of Dendrite-Like Processes |
| Alternative Protein Names | Interleukin-1 Receptor Accessory Protein-Like 1 proteinIl-1-Rapl-1 proteinIl-1rapl-1 proteinIl1rapl-1 proteinOligophrenin-4 proteinThree Immunoglobulin Domain-Containing Il-1 Receptor-Related 2 proteinTigirr-2 proteinX-Linked Interleukin-1 Receptor Accessory Protein-Like 1 proteinIL1RAPL1 proteinOPHN4 protein |
Information sourced from Uniprot.org