Name: Human IL17RD protein (Recombinant) (C-Fc) (STJP013532)
SKU: STJP013532-100
Price: 575.5 GBP
Availability: InStock

Human IL17RD protein (Recombinant) (C-Fc) (STJP013532)

SKU:

STJP013532-100

£575.50

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Host:	Mammalian Cells
Applications:	ELISA/WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human IL17RD-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.

Conjugation:	Unconjugated
Formulation:	Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Dilution Range:	Reconstitute in sterile water for a stock solution.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:	< 1 EU/µg as determined by LAL test.

Function	Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Might have a role in the early stages of fate specification of GnRH-secreting neurons. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells.
Protein Name	Interleukin-17 Receptor D Il-17 Receptor D Il-17rd Il17rhom Interleukin-17 Receptor-Like Protein Sef Homolog Hsef
Database Links	Reactome: R-HSA-5674135
Cellular Localisation	Golgi Apparatus Membrane Single-Pass Type I Membrane Protein Cell Membrane Predominantly Associated With The Golgi Apparatus And Is Partially Translocated To The Plasma Membrane Upon Stimulation Isoform 4: Cytoplasm
Alternative Protein Names	Interleukin-17 Receptor D protein Il-17 Receptor D protein Il-17rd protein Il17rhom protein Interleukin-17 Receptor-Like Protein protein Sef Homolog protein Hsef protein IL17RD protein IL17RLM protein SEF protein UNQ6115 protein PRO20026 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP013981	Mouse IL17RD protein (Recombinant) (C-Fc) (STJP013981)	Mammalian Cells	ELISA/WB
STJP013531	Human IL17RD protein (Recombinant) (C-His) (STJP013531)	Mammalian Cells	ELISA/WB
STJP013980	Mouse IL17RD protein (Recombinant) (C-His) (STJP013980)	Mammalian Cells	ELISA/WB
STJP004445	Human CD27 protein (Recombinant) (C-Fc) (STJP004445)	Mammalian Cells
STJP006752	Human DSG3 protein (Recombinant) (C-Fc) (STJP006752)	Mammalian Cells

Human IL17RD protein (Recombinant) (C-Fc) (STJP013532)

General Information