Name: Human IL16 protein (Recombinant) (N-His-SUMO) (STJP009050)
SKU: STJP009050
Availability: InStock

Human IL16 protein (Recombinant) (N-His-SUMO) (STJP009050)

SKU:

STJP009050

£208.50 - £1,163.50

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Short Description :	Recombinant-Human IL16-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	Isoform 3: Synthesized as a chemo-attractant inactive precursor in hemopoietic tissues, and proteolytically cleaved by caspase-3 to yield IL-16.
Function	Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. Isoform 1: May act as a scaffolding protein that anchors ion channels in the membrane. Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
Protein Name	Pro-Interleukin-16 Cleaved Into - Interleukin-16 Il-16 Lymphocyte Chemoattractant Factor Lcf
Database Links	Reactome: R-HSA-449836
Cellular Localisation	Interleukin-16: Secreted Isoform 1: Cytoplasm Isoform 3: Cytoplasm Nucleus
Alternative Protein Names	Pro-Interleukin-16 Cleaved Into - Interleukin-16 protein Il-16 protein Lymphocyte Chemoattractant Factor protein Lcf protein IL16 protein

Information sourced from Uniprot.org

Human IL16 protein (Recombinant) (N-His-SUMO) (STJP009050)

General Information

Model	Name	Host	Application
STJP005372	Human IL16 protein (Recombinant) (N-His) (STJP005372)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP003590	Human APOA2 protein (Recombinant) (N-His-SUMO) (STJP003590)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP004668	Human GDNF protein (Recombinant) (N-His-SUMO) (STJP004668)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP003879	Human FGF2 protein (Recombinant) (N-His-SUMO) (STJP003879)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP008815	Human SAA1 protein (Recombinant) (N-His-SUMO) (STJP008815)	E.coli	ELISA/Immunogen/SDS-PAGE/WB