Human IL12Rb2 (Interleukin 12 Receptor Beta 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016158)

Human IL12Rb2 (Interleukin 12 Receptor Beta 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016158)

SKU:
STJE0016158
€514.38 - €700.63
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This IL12Rb2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: IL12RB2
Gene ID: 3595
Uniprot ID: I12R2_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Isoform 2 is expressed at similar levels in both naive and activated T-cells.
Post Translational Modifications On IL12 binding, phosphorylated on C-terminal tyrosine residues by JAK2. Phosphorylation on Tyr-800 is required for STAT4 binding and activation, and for SOCS3 binding.
Function Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
Protein Name Interleukin-12 Receptor Subunit Beta-2
Il-12 Receptor Subunit Beta-2
Il-12r Subunit Beta-2
Il-12r-Beta-2
Il-12rb2
Database Links Reactome: R-HSA-8984722
Reactome: R-HSA-9020591
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative ELISA Names Interleukin-12 Receptor Subunit Beta-2 ELISA kit
Il-12 Receptor Subunit Beta-2 ELISA kit
Il-12r Subunit Beta-2 ELISA kit
Il-12r-Beta-2 ELISA kit
Il-12rb2 ELISA kit
IL12RB2 ELISA kit
output

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJE0009774 Human IL12Rb2 (Interleukin 12 Receptor Beta 2) Sandwich ELISA Kit Kit (STJE0009774) Human ELISA
STJE0016157 Human IL12Rb1 (Interleukin 12 Receptor Beta 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016157) Human ELISA
STJE0016298 Human IL2Rg (Interleukin 2 Receptor Gamma) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016298) Human ELISA
STJE0016374 Rat IL8Rb (Interleukin 8 Receptor Beta) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016374) Rat ELISA
STJE0013338 Human ADRb2 (Adrenergic Receptor Beta 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013338) Human ELISA
!