Human IL-2 R alpha/CD25 protein (Recombinant) (C-His&Avi) (STJP019909)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human IL-2 R alpha/CD25 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu22-Cys213) of Human IL-2 R alpha/CD25 (Accession #P01589) fused with a C-His&Avi tag at the C-terminus.
General Information
| Short Description | Recombinant-Human IL-2 R alpha/CD25-C-His&Avi protein was developed in hek293 cells using the region Glu22-Cys213. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | IL2RA |
| Gene ID | 3559 |
| Uniprot ID | IL2RA_HUMAN |
| Immunogen | Recombinant Human IL-2 R alpha/CD25 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu22-Cys213) of Human IL-2 R alpha/CD25 (Accession #P01589) fused with a C-His&Avi tag at the C-terminus. |
| Immunogen Region | Glu22-Cys213 |
| Immunogen Sequence | ELCDDDPPEIPHATFKAMAY KEGTMLNCECKRGFRRIKSG SLYMLCTGNSSHSSWDNQCQ CTSSATRNTTKQVTPQPEEQ KERKTTEMQSPMQPVDQASL PGHCREPPPWENEATERIYH FVVGQMVYYQCVQGYRALHR GPAESVCKMTHGKTRWTQPQ LICTGEMETSQFPGEEKPQA SPEGRPESETSC |
Additional Info
| Function | Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. |
| Protein Name | Interleukin-2 Receptor Subunit AlphaIl-2 Receptor Subunit AlphaIl-2-RaIl-2r Subunit AlphaIl2-RaTac AntigenP55Cd Antigen Cd25 |
| Database Links | Reactome: R-HSA-5673001Reactome: R-HSA-8877330Reactome: R-HSA-9020558Reactome: R-HSA-912526 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-2 Receptor Subunit Alpha proteinIl-2 Receptor Subunit Alpha proteinIl-2-Ra proteinIl-2r Subunit Alpha proteinIl2-Ra proteinTac Antigen proteinP55 proteinCd Antigen Cd25 proteinIL2RA protein |
Information sourced from Uniprot.org