Human IL-13RA1/CD213a1 protein (Recombinant) (C-His) (STJP001112)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human IL-13RA1/CD213a1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met 1-Thr 343) of human IL13RA1 (Accession #NP_001551.1) fused with a 6ΓHis tag at the C-terminus.
General Information
| Short Description | Recombinant-Human IL-13RA1/CD213a1-C-His protein was developed in hek293 cells using the region Met 1-Thr 343. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | IL13RA1 |
| Gene ID | 3597 |
| Uniprot ID | I13R1_HUMAN |
| Immunogen | Recombinant Human IL-13RA1/CD213a1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met 1-Thr 343) of human IL13RA1 (Accession #NP_001551.1) fused with a 6ΓHis tag at the C-terminus. |
| Immunogen Region | Met 1-Thr 343 |
| Immunogen Sequence | MEWPARLCGLWALLLCAGGG GGGGGAAPTETQPPVTNLSV SVENLCTVIWTWNPPEGASS NCSLWYFSHFGDKQDKKIAP ETRRSIEVPLNERICLQVGS QCSTNESEKPSILVEKCISP PEGDPESAVTELQCIWHNLS YMKCSWLPGRNTSPDTNYTL YYWHRSLEKIHQCENIFREG QYFGCSFDLTKVKDSSFEQH SVQIMVKDNAGKIKPSFNIV PLTSRVKPDPPHIKNLSFH |
Additional Info
| Function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
| Protein Name | Interleukin-13 Receptor Subunit Alpha-1Il-13 Receptor Subunit Alpha-1Il-13r Subunit Alpha-1Il-13r-Alpha-1Il-13ra1Cancer/Testis Antigen 19Ct19Cd Antigen Cd213a1 |
| Database Links | Reactome: R-HSA-6785807 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-13 Receptor Subunit Alpha-1 proteinIl-13 Receptor Subunit Alpha-1 proteinIl-13r Subunit Alpha-1 proteinIl-13r-Alpha-1 proteinIl-13ra1 proteinCancer/Testis Antigen 19 proteinCt19 proteinCd Antigen Cd213a1 proteinIL13RA1 proteinIL13R proteinIL13RA protein |
Information sourced from Uniprot.org