Human IL-13RA1/CD213a1 protein (Recombinant) (C-His&Avi) {Biotin} (STJP020233)

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STJP020233-100
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Covered by St John's Laboratory Guarantee

Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Biotin
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Gene Symbol: IL13RA1
Gene ID: 3597
Uniprot ID: I13R1_HUMAN
Immunogen Region: Ala27-Thr343
Immunogen: Biotinylated Recombinant Human IL-13RA1/CD213a1 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ala27-Thr343) of Human IL-13RA1/CD213a1 fused with a His and Avi tag at the C-terminal.
Tissue Specificity Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary.lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.
Function Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Protein Name Interleukin-13 Receptor Subunit Alpha-1
Il-13 Receptor Subunit Alpha-1
Il-13r Subunit Alpha-1
Il-13r-Alpha-1
Il-13ra1
Cancer/Testis Antigen 19
Ct19
Cd Antigen Cd213a1
Database Links Reactome: R-HSA-6785807
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-13 Receptor Subunit Alpha-1 protein
Il-13 Receptor Subunit Alpha-1 protein
Il-13r Subunit Alpha-1 protein
Il-13r-Alpha-1 protein
Il-13ra1 protein
Cancer/Testis Antigen 19 protein
Ct19 protein
Cd Antigen Cd213a1 protein
IL13RA1 protein
IL13R protein
IL13RA protein

Information sourced from Uniprot.org

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