Human IL-13R alpha 2/IL13RA2 protein (Recombinant) (His-Tag) (STJP018246)

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STJP018246
€161.40 - €886.20
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Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IL-13R alpha 2/IL13RA2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL13RA2
Gene ID: 3598
Uniprot ID: I13R2_HUMAN
Immunogen Region: 27-343aa
Accession Number: NP_000631
Immunogen: Human
Immunogen Sequence: DTEIKVN PPQDFEIVDP GYLGYLYLQW QPPLSLDHFK ECTVEYELKY RNIGSETWKT IITKNLHYKD GFDLNKGIEA KIHTLLPWQC TNGSEVQSSW AETTYWISPQ GIPETKVQDM DCVYYNWQYL LCSWKPGIGV LLDTNYNLFY WYEGLDHALQ CVDYIKADGQ NIGCRFPYLE ASDYKDFYIC VNGSSENKPI RSSYFT
Post Translational Modifications Cleaved by MMP8 leading to a soluble form that is also able to interact with IL13.
Function Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1.
Protein Name Interleukin-13 Receptor Subunit Alpha-2
Il-13 Receptor Subunit Alpha-2
Il-13r Subunit Alpha-2
Il-13r-Alpha-2
Il-13ra2
Interleukin-13-Binding Protein
Cd Antigen Cd213a2
Database Links Reactome: R-HSA-6785807
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-13 Receptor Subunit Alpha-2 protein
Il-13 Receptor Subunit Alpha-2 protein
Il-13r Subunit Alpha-2 protein
Il-13r-Alpha-2 protein
Il-13ra2 protein
Interleukin-13-Binding Protein protein
Cd Antigen Cd213a2 protein
IL13RA2 protein
IL13R protein

Information sourced from Uniprot.org

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