| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Human IGFBP6-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Gene Symbol: | IGFBP6 |
| Gene ID: | 3489 |
| Uniprot ID: | IBP6_HUMAN |
| Immunogen Region: | Ala25-Gly240 |
| Immunogen: | Homo sapiens (Human) |
| Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration. |
| Protein Name | Insulin-Like Growth Factor-Binding Protein 6Ibp-6Igf-Binding Protein 6Igfbp-6 |
| Database Links | Reactome: R-HSA-381426 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Insulin-Like Growth Factor-Binding Protein 6 proteinIbp-6 proteinIgf-Binding Protein 6 proteinIgfbp-6 proteinIGFBP6 proteinIBP6 protein |
Information sourced from Uniprot.org
