Name: Human IGFBP1 protein (Recombinant) (N-His) (STJP003870)
SKU: STJP003870
Availability: InStock

Human IGFBP1 protein (Recombinant) (N-His) (STJP003870)

SKU:

STJP003870

$287.73 - $1,605.63

Free Shipping

Short Description :	Recombinant-Human IGFBP1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Multifunctional protein that plays a critical role in regulating the availability of IGFs such as IGF1 and IGF2 to their receptors and thereby regulates IGF-mediated cellular processes including cell migration, proliferation, differentiation or apoptosis in a cell-type specific manner. Also plays a positive role in cell migration by interacting with integrin ITGA5:ITGB1 through its RGD motif. Mechanistically, binding to integrins leads to activation of focal adhesion kinase/PTK2 and stimulation of the mitogen-activated protein kinase (MAPK) pathway. Regulates cardiomyocyte apoptosis by suppressing HIF-1alpha/HIF1A ubiquitination and subsequent degradation.
Protein Name	Insulin-Like Growth Factor-Binding Protein 1 Ibp-1 Igf-Binding Protein 1 Igfbp-1 Placental Protein 12 Pp12
Database Links	Reactome: R-HSA-380994 Reactome: R-HSA-381426 Reactome: R-HSA-8957275 Reactome: R-HSA-9615017
Cellular Localisation	Secreted
Alternative Protein Names	Insulin-Like Growth Factor-Binding Protein 1 protein Ibp-1 protein Igf-Binding Protein 1 protein Igfbp-1 protein Placental Protein 12 protein Pp12 protein IGFBP1 protein IBP1 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP010007	Human IGFBP1 protein (Recombinant) (C-His) (STJP010007)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP003871	Human IGFBP1 protein (Recombinant) (C-His) (STJP003871)	Mammalian Cells	ELISA/Immunogen/SDS-PAGE/WB
STJP009169	Mouse IGFBP1 protein (Recombinant) (N-His-SUMO) (STJP009169)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP011830	Human IGFBP1 protein (Recombinant-Active) (C-His) (STJP011830)	Mammalian Cells	ELISA/WB
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen

Human IGFBP1 protein (Recombinant) (N-His) (STJP003870)

General Information