Human IFNGR2 protein (Recombinant) (N-His) (STJP008341)

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STJP008341
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IFNGR2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IFNGR2
Gene ID: 3460
Uniprot ID: INGR2_HUMAN
Immunogen Region: Lys37-Asp240
Immunogen: Homo sapiens (Human)
Function Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding.
Protein Name Interferon Gamma Receptor 2
Ifn-Gamma Receptor 2
Ifn-Gamma-R2
Interferon Gamma Receptor Accessory Factor 1
Af-1
Interferon Gamma Receptor Beta-Chain
Ifn-Gamma-R-Beta
Interferon Gamma Transducer 1
Database Links Reactome: R-HSA-877300
Reactome: R-HSA-877312
Reactome: R-HSA-9679191
Reactome: R-HSA-9732724
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cytoplasmic Vesicle Membrane
Golgi Apparatus Membrane
Endoplasmic Reticulum Membrane
Cytoplasm
Has Low Cell Surface Expression And High Cytoplasmic Expression In T Cells
The Bias Towards Cytoplasmic Expression May Be Due To Ligand-Independent Receptor Internalization And Recycling
Alternative Protein Names Interferon Gamma Receptor 2 protein
Ifn-Gamma Receptor 2 protein
Ifn-Gamma-R2 protein
Interferon Gamma Receptor Accessory Factor 1 protein
Af-1 protein
Interferon Gamma Receptor Beta-Chain protein
Ifn-Gamma-R-Beta protein
Interferon Gamma Transducer 1 protein
IFNGR2 protein
IFNGT1 protein

Information sourced from Uniprot.org