Human IFN-alpha 10 protein (Recombinant) (C-Avi&His) (STJP003023)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human IFN-alpha 10 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys24-Asp189) of Human IFN-alpha 10/IFNA10 (Accession #NP_002162.1) fused with a Flag at the C-terminus.
General Information
| Short Description | Recombinant-Human IFN-alpha 10-C-Avi&His protein was developed in hek293 cells using the region Cys24-Asp189. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured in a cell cytotoxicity assay using TF-1 cells. The ED50 for this effect is 0.26โ1.04 ng/mL, corresponding to a specific activity of 9.62ร105~3.85ร106 units/mg. |
| Determination Method | <1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | IFNA10 |
| Gene ID | 3446 |
| Uniprot ID | IFN10_HUMAN |
| Immunogen | Recombinant Human IFN-alpha 10 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys24-Asp189) of Human IFN-alpha 10/IFNA10 (Accession #NP_002162.1) fused with a Flag at the C-terminus. |
| Immunogen Region | Cys24-Asp189 |
| Immunogen Sequence | LQVDIVPSQGEISVGESKFF LCQVAGDAKDKDISWFSPNG EKLSPNQQRISVVWNDDDSS TLTIYNANIDDAGIYKCVVT AEDGTQSEATVNVKIFQKLM FKNAPTPQEFKEGEDAVIVC DVVSSLPPTIIWKHKGRDVI LKKDVRFIVLSNNYLQIRGI KKTDEGTYRCEGRILARGEI NFKDIQVIVNVPPTVQARQS IVNATANLGQSVTLVCDADG FPEPTMSWTKDGEPIENEE |
Additional Info
| Function | Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. |
| Protein Name | Interferon Alpha-10Ifn-Alpha-10Interferon Alpha-6lInterferon Alpha-CLeif C |
| Database Links | Reactome: R-HSA-909733Reactome: R-HSA-912694Reactome: R-HSA-933541Reactome: R-HSA-9705671Reactome: R-HSA-983231Reactome: R-HSA-9833109 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Interferon Alpha-10 proteinIfn-Alpha-10 proteinInterferon Alpha-6l proteinInterferon Alpha-C proteinLeif C proteinIFNA10 protein |
Information sourced from Uniprot.org