Human IFN-alpha 1/13 (Q114A) protein (Recombinant) (C-His) (STJP000785)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenRecombinant Human IFN-alpha 1/13 (Q114A) Protein is produced by E. coli expression system. The target protein is expressed with sequence (Cys24-Glu189 (Ala114) ) of human IFNA1 (Accession #NP_076918.1) fused with an initial Met at the N-terminus and
General Information
| Short Description | Recombinant-Human IFN-alpha 1/13 (Q114A)-C-His protein was developed in e.coli using the region Cys24-Glu189. For use in research applications. |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured by its ability to stimulate GBP2 expression in 293T human embryonic kidney cells. 0.1-1 ng/mL of Recombinant Human IFNA1 can effectively Stimulating GBP2 expression.|2.Measured by its ability to stimulate human colon adenocarcinoma cells (Ca |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | IFNA1.IFNA13 |
| Gene ID | 3439/3447 |
| Uniprot ID | IFNA1_HUMAN |
| Immunogen | Recombinant Human IFN-alpha 1/13 (Q114A) Protein is produced by E. coli expression system. The target protein is expressed with sequence (Cys24-Glu189 (Ala114) ) of human IFNA1 (Accession #NP_076918.1) fused with an initial Met at the N-terminus and |
| Immunogen Region | Cys24-Glu189 |
| Immunogen Sequence | CDLPETHSLDNRRTLMLLAQ MSRISPSSCLMDRHDFGFPQ EEFDGNQFQKAPAISVLHEL IQQIFNLFTTKDSSAAWDED LLDKFCTELYAQLNDLEACV MQEERVGETPLMNADSILAV KKYFRRITLYLTEKKYSPCA WEVVRAEIMRSLSLSTNLQE RLRRKE |
Additional Info
| Function | Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. |
| Protein Name | Interferon Alpha-1/13Ifn-Alpha-1/13Interferon Alpha-DLeif D |
| Database Links | Reactome: R-HSA-909733Reactome: R-HSA-912694Reactome: R-HSA-933541Reactome: R-HSA-9705671Reactome: R-HSA-983231Reactome: R-HSA-9833109 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Interferon Alpha-1/13 proteinIfn-Alpha-1/13 proteinInterferon Alpha-D proteinLeif D proteinIFNA1.IFNA13 protein |
Information sourced from Uniprot.org