Human IER3 protein (Recombinant) (N-GST & C-His) (STJP016309)

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STJP016309
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Short Description :Recombinant-Human IER3-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact us for further information.
Gene Symbol:IER3
Gene ID:8870
Uniprot ID:IEX1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met100-Phe156
Function May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Also acts as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
Protein Name Radiation-Inducible Immediate-Early Gene Iex-1
Differentiation-Dependent Gene 2 Protein
Protein Dif-2
Immediate Early Protein Gly96
Immediate Early Response 3 Protein
Pacap-Responsive Gene 1 Protein
Protein Prg1
Database Links Reactome: R-HSA-6811558
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Radiation-Inducible Immediate-Early Gene Iex-1 protein
Differentiation-Dependent Gene 2 Protein protein
Protein Dif-2 protein
Immediate Early Protein Gly96 protein
Immediate Early Response 3 Protein protein
Pacap-Responsive Gene 1 Protein protein
Protein Prg1 protein
IER3 protein
DIF2 protein
IEX1 protein
PRG1 protein

Information sourced from Uniprot.org