| Short Description : | Recombinant-Active-Human ICAM5-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by the ability of the Immobilised protein to support the adhesion of PMA-stimulated human peripheral blood acute lymphoblastic leukemia cells (HSB2). When 5 x 10^4 cells/well are added to recombinant human ICAM5 coated plates (25 µg/mL, 100 |
| Gene Symbol: | ICAM5 |
| Gene ID: | 7087 |
| Uniprot ID: | ICAM5_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ala28-Glu570 |
| Post Translational Modifications | Glycosylation at Asn-54 is critical for functional folding. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). |
| Protein Name | Intercellular Adhesion Molecule 5Icam-5Telencephalin |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Intercellular Adhesion Molecule 5 proteinIcam-5 proteinTelencephalin proteinICAM5 proteinTLCN proteinTLN protein |
Information sourced from Uniprot.org