| Host: | HEK293 Cells |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human ICAM-5-hIgG-His-Tag protein was developed from hek293 cells and has a target region of hIgG-His-Tag. For use in research applications. |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Gene Symbol: | ICAM5 |
| Gene ID: | 7087 |
| Uniprot ID: | ICAM5_HUMAN |
| Immunogen Region: | 23-835aa |
| Accession Number: | NP_003250 |
| Immunogen: | Human |
| Immunogen Sequence: | LFGLSAVSQE PFWADLQPRV AFVERGGSLW LNCSTNCPRP ERGGLETSLR RNGTQRGLRW LARQLVDIRE PETQPVCFFR CARRTLQARG LIRTFQRPDR VELMPLPPWQ PVGENFTLSC RVPGAGPRAS LTLTLLRGAQ ELIRRSFAGE PPRARGAVLT ATVLARREDH GANFSCRAEL DLRPHGLGLF ENSSAPRELR TFSLSPDAPR LAAPRLLEVG SERPVSCT |
| Tissue Specificity | Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon. |
| Post Translational Modifications | Glycosylation at Asn-54 is critical for functional folding. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). |
| Protein Name | Intercellular Adhesion Molecule 5Icam-5Telencephalin |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Intercellular Adhesion Molecule 5 proteinIcam-5 proteinTelencephalin proteinICAM5 proteinTLCN proteinTLN protein |
Information sourced from Uniprot.org