Human IAPP protein (Recombinant) (N-His-SUMO) (STJP008895)

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STJP008895
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IAPP-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IAPP
Gene ID: 3375
Uniprot ID: IAPP_HUMAN
Immunogen Region: Thr23-Leu89
Immunogen: Homo sapiens (Human)
Function Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis. Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes. Amylin can also bind CALCR receptor in the absence of RAMPs, although it is more selective for AMYRs.
Protein Name Islet Amyloid Polypeptide
Iapp
Amylin
Diabetes-Associated Peptide
Dap
Insulinoma Amyloid Peptide
Database Links Reactome: R-HSA-210745
Reactome: R-HSA-418555
Reactome: R-HSA-419812
Reactome: R-HSA-977225
Cellular Localisation Secreted
Alternative Protein Names Islet Amyloid Polypeptide protein
Iapp protein
Amylin protein
Diabetes-Associated Peptide protein
Dap protein
Insulinoma Amyloid Peptide protein
IAPP protein

Information sourced from Uniprot.org