Human HTR4 (5-Hydroxytryptamine Receptor 4) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015985)

Human HTR4 (5-Hydroxytryptamine Receptor 4) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015985)

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STJE0015985
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.063ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This HTR4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: HTR4
Gene ID: 3360
Uniprot ID: 5HT4R_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Isoform 5-HT4(A): Expressed in ileum, brain, and atrium, but not in the ventricle. Isoform 5-HT4(E): Mainly expressed in atria and cardiac ventricle. Isoform 5-HT4(I): Expressed in all cardiovascular tissues analyzed.
Post Translational Modifications
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR4 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity.
Protein Name 5-Hydroxytryptamine Receptor 4
5-Ht-4
5-Ht4
Serotonin Receptor 4
Database Links Reactome: R-HSA-390666
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Endosome Membrane
Interaction With Snx27 Mediates Recruitment To Early Endosomes
While Interaction With Nherf1 And Ezr Might Target The Protein To Specialized Subcellular Regions
Such As Microvilli
Alternative ELISA Names 5-Hydroxytryptamine Receptor 4 ELISA kit
5-Ht-4 ELISA kit
5-Ht4 ELISA kit
Serotonin Receptor 4 ELISA kit
HTR4 ELISA kit
output

Information sourced from Uniprot.org

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