| Post Translational Modifications | The N-terminus is blocked. Phosphorylated at Ser-16 by PKA and probably PKD1K.required to protect cardiomyocytes from apoptosis. |
| Function | Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity. |
| Protein Name | Heat Shock Protein Beta-6Hspb6Heat Shock 20 Kda-Like Protein P20Heat Shock Protein Family B Member 6 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusSecretedTranslocates To Nuclear Foci During Heat Shock |
| Alternative Protein Names | Heat Shock Protein Beta-6 proteinHspb6 proteinHeat Shock 20 Kda-Like Protein P20 proteinHeat Shock Protein Family B Member 6 proteinHSPB6 protein |
Information sourced from Uniprot.org
