Human HSD17B3 protein (Recombinant) (N-His) (STJP006615)

SKU:
STJP006615
£208.50 - £1,163.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Recombinant-Human HSD17B3-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:HSD17B3
Gene ID:3293
Uniprot ID:DHB3_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met1-Arg310
Function Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids. Favors the reduction of androstenedione to testosterone. Testosterone is the key androgen driving male development and function. Uses NADPH while the two other EDH17B enzymes use NADH. Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17. Can reduce 11-ketoandrostenedione as well as 11beta-hydroxyandrostenedione at C-17 to the respective testosterone forms.
Protein Name 17-Beta-Hydroxysteroid Dehydrogenase Type 3
17-Beta-Hsd 3
Estradiol 17-Beta-Dehydrogenase 2
Short Chain Dehydrogenase/Reductase Family 12c Member 2
Testicular 17-Beta-Hydroxysteroid Dehydrogenase
Testosterone 17-Beta-Dehydrogenase 3
Database Links Reactome: R-HSA-193048
Reactome: R-HSA-75876
Cellular Localisation Endoplasmic Reticulum
Alternative Protein Names 17-Beta-Hydroxysteroid Dehydrogenase Type 3 protein
17-Beta-Hsd 3 protein
Estradiol 17-Beta-Dehydrogenase 2 protein
Short Chain Dehydrogenase/Reductase Family 12c Member 2 protein
Testicular 17-Beta-Hydroxysteroid Dehydrogenase protein
Testosterone 17-Beta-Dehydrogenase 3 protein
HSD17B3 protein
EDH17B3 protein
SDR12C2 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E.coli SDS-PAGE/WB/ELISA/Immunogen
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP015118 Human TAS1R1 protein protein (Recombinant) (N-His) (STJP015118) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP014345 Human HBZ protein (Recombinant) (N-His) (STJP014345) E.coli ELISA/WB
STJP014302 Human ALDH1A2 protein (Recombinant) (N-His) (STJP014302) E.coli ELISA/WB

Related Products

!