Human HPS6 protein (Recombinant) (N-His-SUMO) (STJP008768)

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STJP008768
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HPS6-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HPS6
Gene ID: 79803
Uniprot ID: HPS6_HUMAN
Immunogen Region: Thr371-Met454
Immunogen: Homo sapiens (Human)
Function May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Acts as a cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning.
Protein Name Bloc-2 Complex Member Hps6
Hermansky-Pudlak Syndrome 6 Protein
Ruby-Eye Protein Homolog
Ru
Cellular Localisation Microsome Membrane
Cytoplasm
Cytosol
Early Endosome Membrane
Lysosome Membrane
Alternative Protein Names Bloc-2 Complex Member Hps6 protein
Hermansky-Pudlak Syndrome 6 Protein protein
Ruby-Eye Protein Homolog protein
Ru protein
HPS6 protein

Information sourced from Uniprot.org

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