Human HPGDS protein (Recombinant) (Tag free) (STJP014282)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HPGDS-Tag free protein was developed from e.coli and has a target region of Tag free. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 200mM NaCl, pH 7.0. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | HPGDS |
| Gene ID | 27306 |
| Uniprot ID | HPGDS_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Leu199 |
Additional Info
| Function | Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. |
| Protein Name | Hematopoietic Prostaglandin D SynthaseH-PgdsGst Class-SigmaGlutathione S-TransferaseGlutathione-Dependent Pgd SynthaseGlutathione-Requiring Prostaglandin D SynthaseProstaglandin-H2 D-Isomerase |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-2162123 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Hematopoietic Prostaglandin D Synthase proteinH-Pgds proteinGst Class-Sigma proteinGlutathione S-Transferase proteinGlutathione-Dependent Pgd Synthase proteinGlutathione-Requiring Prostaglandin D Synthase proteinProstaglandin-H2 D-Isomerase proteinHPGDS proteinGSTS proteinPGDS proteinPTGDS2 protein |
Information sourced from Uniprot.org