Human HNF4A protein (Recombinant) (N-His) (STJP004699)

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STJP004699
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HNF4A-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HNF4A
Gene ID: 3172
Uniprot ID: HNF4A_HUMAN
Immunogen Region: Gln131-Ser330
Immunogen: Homo sapiens (Human)
Function Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes. Activates the transcription of CYP2C38. Represses the CLOCK-BMAL1 transcriptional activity and is essential for circadian rhythm maintenance and period regulation in the liver and colon cells.
Protein Name Hepatocyte Nuclear Factor 4-Alpha
Hnf-4-Alpha
Nuclear Receptor Subfamily 2 Group A Member 1
Transcription Factor 14
Tcf-14
Transcription Factor Hnf-4
Database Links Reactome: R-HSA-210745
Reactome: R-HSA-383280
Reactome: R-HSA-9831926
Cellular Localisation Nucleus
Alternative Protein Names Hepatocyte Nuclear Factor 4-Alpha protein
Hnf-4-Alpha protein
Nuclear Receptor Subfamily 2 Group A Member 1 protein
Transcription Factor 14 protein
Tcf-14 protein
Transcription Factor Hnf-4 protein
HNF4A protein
HNF4 protein
NR2A1 protein
TCF14 protein

Information sourced from Uniprot.org

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