Human HMGN1 protein (Recombinant) (N-His) (STJP003704)

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STJP003704
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HMGN1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HMGN1
Gene ID: 3150
Uniprot ID: HMGN1_HUMAN
Immunogen Region: Lys14-Asp100
Immunogen: Homo sapiens (Human)
Function Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2.
Protein Name Non-Histone Chromosomal Protein Hmg-14
High Mobility Group Nucleosome-Binding Domain-Containing Protein 1
Cellular Localisation Nucleus
Cytoplasm
Cytoplasmic Enrichment Upon Phosphorylation
The Rna Edited Version Localizes To The Nucleus
Alternative Protein Names Non-Histone Chromosomal Protein Hmg-14 protein
High Mobility Group Nucleosome-Binding Domain-Containing Protein 1 protein
HMGN1 protein
HMG14 protein

Information sourced from Uniprot.org