Human Histamine N-Methyltransferase/HNMT protein (Recombinant) (His-Tag) (STJP019369)

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STJP019369
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Short Description :Recombinant-Human Histamine N-Methyltransferase/HNMT-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Enzyme Activity
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Immunoreactivity:Specific activity is > 200nmol/min/mg, and is defined as the amount of enzyme that transfer 1.0nmole of methyl group per minute at 37C
Gene Symbol:HNMT
Gene ID:3176
Uniprot ID:HNMT_HUMAN
Accession Number:AAH20677
Immunogen:Human
Immunogen Region:1-292aa
Immunogen Sequence:MASS MRSLFSDHGK YVESFRRFLN HSTEHQCMQE FMDKKLPGII GRIGDTKSEI KILSIGGGAG EIDLQILSKV QAQYPGVCIN NEVVEPSAEQ IAKYKELVAK TSNLENVKFA WHKETSSEYQ SRMLEKKELQ KWDFIHMIQM LYYVKDIPAT LKFFHSLLGT NAKMLIIVVS GSSGWDKLWK KYGSRF
Function Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
Protein Name Histamine N-Methyltransferase
Hmt
Database Links Reactome: R-HSA-2408508
Reactome: R-HSA-70921
Cellular Localisation Cytoplasm
Alternative Protein Names Histamine N-Methyltransferase protein
Hmt protein
HNMT protein

Information sourced from Uniprot.org