Human HIP1R protein (Recombinant) (N-His) (STJP003342)

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STJP003342
€410.63 - €1,796.88
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HIP1R-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HIP1R
Gene ID: 9026
Uniprot ID: HIP1R_HUMAN
Immunogen Region: Ser771-Ala1012
Immunogen: Homo sapiens (Human)
Function Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
Protein Name Huntingtin-Interacting Protein 1-Related Protein
Hip1-Related Protein
Huntingtin-Interacting Protein 12
Hip-12
Database Links Reactome: R-HSA-432722
Reactome: R-HSA-8856828
Cellular Localisation Cytoplasm
Perinuclear Region
Endomembrane System
Cytoplasmic Vesicle
Clathrin-Coated Vesicle Membrane
Membrane-Associated Protein
Mainly Localized At The Endocytic Compartments And In The Perinuclear Region
Alternative Protein Names Huntingtin-Interacting Protein 1-Related Protein protein
Hip1-Related Protein protein
Huntingtin-Interacting Protein 12 protein
Hip-12 protein
HIP1R protein
HIP12 protein
KIAA0655 protein

Information sourced from Uniprot.org

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