Human HIBCH protein (Recombinant) (His-Tag) (STJP017592)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human HIBCH-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.2M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HIBCH |
| Gene ID | 26275 |
| Uniprot ID | HIBCH_HUMAN |
| Accession Number | NP_055177 |
| Immunogen | Human |
| Immunogen Region | 33-386aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMDAAEE VLLEKKGCTG VITLNRPKFL NALTLNMIRQ IYPQLKKWEQ DPETFLIIIK GAGGKAFCAG GDIRVISEAE KAKQKIAPVF FREEYMLNNA VGSCQKPYVA LIHGITMGGG VGLSVHGQFR VATEKCLFAM PETAIGLFPD VGGGYFLPRL QGKLGYFLAL TGFRLKGRDV YRAGIATHFV DSEKLAMLEE DLLALKSP |
Additional Info
| Tissue Specificity | Highly expressed in liver and kidney, also detected in heart, muscle and brain (at protein level). Not detected in lung. |
| Function | Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA. |
| Protein Name | 3-Hydroxyisobutyryl-Coa Hydrolase - Mitochondrial3-Hydroxyisobutyryl-Coenzyme A HydrolaseHib-Coa HydrolaseHibyl-Coa-H |
| Database Links | Reactome: R-HSA-70895Reactome: R-HSA-9916722 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | 3-Hydroxyisobutyryl-Coa Hydrolase - Mitochondrial protein3-Hydroxyisobutyryl-Coenzyme A Hydrolase proteinHib-Coa Hydrolase proteinHibyl-Coa-H proteinHIBCH protein |
Information sourced from Uniprot.org