Human HEPACAM protein (Recombinant) (N-His) (STJP008218)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HEPACAM-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | HEPACAM |
| Gene ID | 220296 |
| Uniprot ID | HECAM_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Arg73-Arg237 |
Additional Info
| Function | Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation. In glia, associates and targets CLCN2 at astrocytic processes and myelinated fiber tracts where it may regulate transcellular chloride flux involved in neuron excitability. |
| Protein Name | Hepatic And Glial Cell Adhesion MoleculeGlialcamHepatocyte Cell Adhesion MoleculeProtein Hepacam |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembraneSingle-Pass Type I Membrane ProteinCytoplasmic SideColocalizes With Clcn2 At Astrocyte End-Foot In Contact With Brain Capillaries And Other Glial CellsIn Mcf-7 Breast Carcinoma And Hepatic Hep 3b21-7 And Hep-G2 Cell LinesLocalization Of Hepacam Is Cell Density-DependentIn Well Spread CellsLocalized To Punctate Structures In The Perinuclear MembraneAnd At Cell Surface Of ProtusionsIn Confluent CellsLocalized Predominantly To The Cytoplasmic MembraneParticularly In Areas Of Cell-Cell ContactsColocalizes With Cdh1 |
| Alternative Protein Names | Hepatic And Glial Cell Adhesion Molecule proteinGlialcam proteinHepatocyte Cell Adhesion Molecule proteinProtein Hepacam proteinHEPACAM protein |
Information sourced from Uniprot.org