Human HEPACAM protein (Recombinant) (N-His) (STJP008218)

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STJP008218
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HEPACAM-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HEPACAM
Gene ID: 220296
Uniprot ID: HECAM_HUMAN
Immunogen Region: Arg73-Arg237
Immunogen: Homo sapiens (Human)
Function Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation. In glia, associates and targets CLCN2 at astrocytic processes and myelinated fiber tracts where it may regulate transcellular chloride flux involved in neuron excitability.
Protein Name Hepatic And Glial Cell Adhesion Molecule
Glialcam
Hepatocyte Cell Adhesion Molecule
Protein Hepacam
Cellular Localisation Cytoplasm
Cell Membrane
Single-Pass Type I Membrane Protein
Cytoplasmic Side
Colocalizes With Clcn2 At Astrocyte End-Foot In Contact With Brain Capillaries And Other Glial Cells
In Mcf-7 Breast Carcinoma And Hepatic Hep 3b2
1-7 And Hep-G2 Cell Lines
Localization Of Hepacam Is Cell Density-Dependent
In Well Spread Cells
Localized To Punctate Structures In The Perinuclear Membrane
And At Cell Surface Of Protusions
In Confluent Cells
Localized Predominantly To The Cytoplasmic Membrane
Particularly In Areas Of Cell-Cell Contacts
Colocalizes With Cdh1
Alternative Protein Names Hepatic And Glial Cell Adhesion Molecule protein
Glialcam protein
Hepatocyte Cell Adhesion Molecule protein
Protein Hepacam protein
HEPACAM protein

Information sourced from Uniprot.org

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