Human HELLS protein (Recombinant) (N-His) (STJP008267)

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STJP008267
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HELLS-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HELLS
Gene ID: 3070
Uniprot ID: HELLS_HUMAN
Immunogen Region: Asp523-His748
Immunogen: Homo sapiens (Human)
Function Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis.
Protein Name Lymphoid-Specific Helicase
Proliferation-Associated Snf2-Like Protein
Swi/Snf2-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 6
Database Links Reactome: R-HSA-9839394
Cellular Localisation Nucleus
Closely Associated With Pericentric Heterochromatin
Alternative Protein Names Lymphoid-Specific Helicase protein
Proliferation-Associated Snf2-Like Protein protein
Swi/Snf2-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 6 protein
HELLS protein
PASG protein
SMARCA6 protein
Nbla10143 protein

Information sourced from Uniprot.org

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