Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human Hedgehog-interacting protein/HHIP-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Gene Symbol: |
HHIP |
Gene ID: |
64399 |
Uniprot ID: |
HHIP_HUMAN |
Immunogen: |
Recombinant Human Hedgehog-interacting protein/HHIP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Phe18-Asp670) of human Hip (Accession #NP_071920.1) fused with a 6×His tag at the C-terminus. |
Tissue Specificity | Widely expressed in fetal and adult tissues. Highest expression in adult heart, liver and pancreas, and in fetal kidney. |
Function | Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family. |
Protein Name | Hedgehog-Interacting ProteinHhipHip |
Database Links | Reactome: R-HSA-5632681 |
Cellular Localisation | Cell MembranePeripheral Membrane ProteinSecretedThe Last 22 C-Terminal Amino Acids May Participate In Cell Membrane AttachmentIsoform 2: Cytoplasm |
Alternative Protein Names | Hedgehog-Interacting Protein proteinHhip proteinHip proteinHHIP proteinHIP proteinUNQ5825 proteinPRO19644 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance