Human HDGF protein (Recombinant) (No-Tag) (STJP016544)

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STJP016544
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Short Description :Recombinant-Human HDGF-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 10% Glycerol, 1mM EDTA
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:HDGF
Gene ID:3068
Uniprot ID:HDGF_HUMAN
Accession Number:NP_004485
Immunogen:Human
Immunogen Region:1-100aa
Immunogen Sequence:MSRSNRQKEY KCGDLVFAKM KGYPHWPARI DEMPEAAVKS TANKYQVFFF GTHETAFLGP KDLFPYEESK EKFGKPNKRK GFSEGLWEIE NNPTVKASGY
Tissue Specificity Ubiquitous.
Post Translational Modifications Sumoylated with SUMO1. Sumoylation prevents binding to chromatin. Phosphorylation at Ser-165 is likely to be required for secretion.
Function Isoform 1: Acts as a transcriptional repressor. Has mitogenic activity for fibroblasts. Heparin-binding protein. Isoform 2: Does not have mitogenic activity for fibroblasts. Does not bind heparin. Isoform 3: Has mitogenic activity for fibroblasts. Heparin-binding protein.
Protein Name Hepatoma-Derived Growth Factor
Hdgf
High Mobility Group Protein 1-Like 2
Hmg-1l2
Database Links Reactome: R-HSA-381038
Cellular Localisation Isoform 1: Nucleus
Cytoplasm
Secreted
Extracellular Exosome
Secreted By Exosomes And Is Located Inside The Exosome
May Also Be Secreted As Free Protein Via An As Yet Unknown Pathway
Isoform 2: Nucleus
Secreted By Exosomes And Is Located On The Outer Exosome Surface
Isoform 3: Nucleus
Alternative Protein Names Hepatoma-Derived Growth Factor protein
Hdgf protein
High Mobility Group Protein 1-Like 2 protein
Hmg-1l2 protein
HDGF protein
HMG1L2 protein

Information sourced from Uniprot.org

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