Name: Human HAX1 protein (Recombinant) (N-GST & C-His) (STJP007670)
SKU: STJP007670
Availability: InStock

Human HAX1 protein (Recombinant) (N-GST & C-His) (STJP007670)

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STJP007670

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human HAX1-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	Proteolytically cleaved by caspase-3 during apoptosis.
Function	Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.
Protein Name	Hcls1-Associated Protein X-1 Hs1-Associating Protein X-1 Hax-1 Hs1-Binding Protein 1 Hsp1bp-1
Cellular Localisation	Mitochondrion Matrix Endoplasmic Reticulum Nucleus Membrane Cytoplasmic Vesicle Cytoplasm Cell Cortex Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Sarcoplasmic Reticulum P-Body Isoform 1: Cytoplasm Nucleus Predominantly Cytoplasmic Also Detected In The Nucleus When Nuclear Export Is Inhibited And In Response To Cellular Stress Caused By Arsenite (In Vitro) Isoform 3: Cytoplasm Also Detected In The Nucleus When Nuclear Export Is Inhibited (In Vitro) Isoform 4: Cytoplasm Shuttles Between Nucleus And Cytoplasm Isoform 5: Cytoplasm
Alternative Protein Names	Hcls1-Associated Protein X-1 protein Hs1-Associating Protein X-1 protein Hax-1 protein Hs1-Binding Protein 1 protein Hsp1bp-1 protein HAX1 protein HS1BP1 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP011289	Human SOX9, N-GST & C-His protein (Recombinant) (N-GST & C-His) (STJP011289)	E. coli
STJP009619	Human WAS protein (Recombinant) (N-GST & C-His) (STJP009619)	E. coli
STJP011634	Human UBAP2 protein (Recombinant) (N-GST & C-His) (STJP011634)	E. coli
STJP005818	Human LEAP2 protein (Recombinant) (N-GST & C-His) (STJP005818)	E. coli
STJP007434	Human NEFH protein (Recombinant) (N-GST & C-His) (STJP007434)	E. coli

Human HAX1 protein (Recombinant) (N-GST & C-His) (STJP007670)

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