Human HAND2 protein (Recombinant) (N-His-KSI) (STJP015419)

SKU:
STJP015419
£222.50 - £1,177.50
Free Shipping
Processing The item has been added

Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HAND2-N-His-KSI protein was developed from e.coli and has a target region of N-His-KSI. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: HAND2
Gene ID: 9464
Uniprot ID: HAND2_HUMAN
Immunogen Region: Ser2-Gln217
Immunogen: Homo sapiens (Human)
Function Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'.
Protein Name Heart- And Neural Crest Derivatives-Expressed Protein 2
Class A Basic Helix-Loop-Helix Protein 26
Bhlha26
Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2
Dhand
Database Links Reactome: R-HSA-8878166
Reactome: R-HSA-9733709
Cellular Localisation Nucleus
Alternative Protein Names Heart- And Neural Crest Derivatives-Expressed Protein 2 protein
Class A Basic Helix-Loop-Helix Protein 26 protein
Bhlha26 protein
Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2 protein
Dhand protein
HAND2 protein
BHLHA26 protein
DHAND protein

Information sourced from Uniprot.org