| Host: |
E. coli |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Recombinant-Human H2AC11-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications. |
| Formulation: |
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Protein Name | Histone H2a Type 1H2a.1Histone H2a/Ptl |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-3214847Reactome: R-HSA-3214858Reactome: R-HSA-5689603Reactome: R-HSA-5689880Reactome: R-HSA-5689901Reactome: R-HSA-9609690Reactome: R-HSA-9610379 |
| Cellular Localisation | NucleusChromosome |
| Alternative Protein Names | Histone H2a Type 1 proteinH2a.1 proteinHistone H2a/Ptl proteinH2AC11 proteinH2AFP proteinHIST1H2AG.H2AC13 proteinH2AFC proteinHIST1H2AI.H2AC15 proteinH2AFD proteinHIST1H2AK.H2AC16 proteinH2AFI proteinHIST1H2AL.H2AC17 proteinH2AFN proteinHIST1H2AM protein |
Information sourced from Uniprot.org
