Human GZMM (Granzyme M) Sandwich ELISA Kit (STJE0009373)

Human GZMM (Granzyme M) Sandwich ELISA Kit (STJE0009373)

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STJE0009373
€535.63 - €731.88
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 5.9pg/mL
Detection Limit: 15.6-1000pg/mL
Short Description : This GZMM Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: GZMM
Gene ID: 3004
Uniprot ID: GRAM_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Highly and constitutively expressed in activated natural killer (NK) cells.
Post Translational Modifications
Function Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
Protein Name Granzyme M
Met-1 Serine Protease
Hu-Met-1
Met-Ase
Natural Killer Cell Granular Protease
Database Links Reactome: R-HSA-173736
Cellular Localisation Secreted
Cytoplasmic Granule
Granules Of Large Granular Lymphocytes
Alternative ELISA Names Granzyme M ELISA kit
Met-1 Serine Protease ELISA kit
Hu-Met-1 ELISA kit
Met-Ase ELISA kit
Natural Killer Cell Granular Protease ELISA kit
GZMM ELISA kit
MET1 ELISA kit
output

Information sourced from Uniprot.org

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